Primary Identifier | MGI:2384574 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235135 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to act upstream of or within innate immune response. Predicted to be located in several cellular components, including Golgi apparatus; endosome; and lysosome. Is expressed in central nervous system; ganglia; gut; olfactory epithelium; and vibrissa. Orthologous to human TMEM45B (transmembrane protein 45B). PHENOTYPE: Mice homozygous for a null allele exhibit reduced long-lasting mechanical pain hypersensitivity in a CFA-induced inflammatory pain model or following surgical tissue incision. [provided by MGI curators] |