| Primary Identifier | MGI:5474852 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 100503605 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable hemoglobin alpha binding activity and hemoglobin beta binding activity. Predicted to contribute to haptoglobin binding activity; oxygen binding activity; and peroxidase activity. Predicted to be located in extracellular space. Predicted to be part of haptoglobin-hemoglobin complex and hemoglobin complex. Is expressed in blood; central nervous system; liver; and retina. Human ortholog(s) of this gene implicated in acute chest syndrome; hemolytic anemia (multiple); malaria; polycythemia (multiple); and sickle cell anemia. Orthologous to several human genes including HBB (hemoglobin subunit beta). |
| specificity | C57BL/6 mice (reference assembly) has a haplotype known as - single, where the two adult beta-globin genes are highly similar to each other, and they are called beta-s (Hbb-bs) and beta-t (Hbb-bt). Other mouse strains such as BALB/c or 129/SvJ have a haplotype known as - diffuse,where the two adult genes, known as beta-major (Hbb-b1) and beta-minor (Hbb-b2), are different from each other (J:32353; J:28981). |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
