Type | MGI:General | Description | mutants exhibit delayed fusion of endocardial cushions; 75% of atrioventricular endocardial cushions are not yet fused at E11.5 78% of E12.5 embryos exhibit rounded atrioventricular endocardial cushion cells with few or no processes instead of the flatted cells with multiple processes seen in wild-type atrioventricular endocardial cushions exhibit increased apoptosis, however show no difference in proliferation stress fibers in endocardial cushions are reduced in size and disorganzied |