| Type | MGI:General | Description | in the Morris water maze, 1 month old mice show a delay in memory acquisition and 3 month old mice completely fail to learn, with mice only rarely finding the hidden platform during probe trials of the Morris water maze, mice spend less time in the target quadrant than controls 3 month old mice treated with doxycycline to turn off transgene expression for 1 week exhibit a similar impairment in memory acquisition in the Morris water maze as untreated mice |