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Publication : Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer.

First Author  Goodenow RS Year  1982
Journal  Nature Volume  300
Issue  5889 Pages  231-7
PubMed ID  6815535 Mgi Jnum  J:6906
Mgi Id  MGI:55378 Doi  10.1038/300231a0
Citation  Goodenow RS, et al. (1982) Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer. Nature 300(5889):231-7
abstractText  DNA-mediated gene transfer was used to identify cloned class I genes from the major histocompatibility complex of the BALB/c mouse. Three genes encoding the transplantation antigens H-2 Kd, Dd and Ld were identified as well as genes encoding the Qa-2,3 and two TL differentiation antigens. As many as 10 putative novel class I genes were detected by the association of their gene products with beta 2-microglobulin. Alloantiserum prepared to one of the novel antigens was used to demonstrate the expression of the previously undetected antigen on spleen cells of various inbred, congeneic, and recombinant congeneic strains of mice.
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