| Type | MGI:General | Description | accumulation of insoluble, phosphorylated cytoplasmic TARDBP+ inclusions in brain and spinal cord is detected as early as 1 week following Dox removal and reaches high levels by 4 weeks accumulation of insoluble TARDBP occurs prior to phosphorylation of protein inclusions are detected in motor cortex, striatum, visual and entorhinal, and somatosensory cortex, cerebellum and hippocampus inclusions are detected in fewer than 2% of spinal cord neurons by disease end stage 28% of neurons contain TARDBP+ puncta |
