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Protein Coding Gene : Actr2 actin related protein 2
Primary Identifier  MGI:1913963 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  66713
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Predicted to enable cytoskeletal protein binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cellular response to type II interferon; meiotic chromosome movement towards spindle pole; and meiotic cytokinesis. Located in actin cap. Is expressed in cochlea and metanephros. Orthologous to human ACTR2 (actin related protein 2).
PHENOTYPE: Mice heterozygous for this mutation exhibit modifies lethality associated with F5 null Tfpi heterozygous mice. [provided by MGI curators]
  • synonyms:
  • D6Ertd746e,
  • MGI:2144001,
  • AA409782,
  • 4921510D23Rik,
  • actin related protein 2,
  • RIKEN cDNA 4921510D23 gene,
  • DNA segment, Chr 6, ERATO Doi 746, expressed,
  • Arp2,
  • expressed sequence AA409782,
  • Actr2,
  • MGI:1289149,
  • MGC:36604
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Genome

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1 Involved In Mutations

Trail: ProteinCodingGene

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

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Homology

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Interactions

18 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

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Disease

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