| Primary Identifier | MGI:2442013 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 319430 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled receptor activity and complement component C5a receptor activity. Predicted to be involved in several processes, including complement receptor mediated signaling pathway; negative regulation of neutrophil chemotaxis; and regulation of cytokine production. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in apical part of cell and basal plasma membrane. Predicted to be active in plasma membrane. Orthologous to human C5AR2 (complement C5a receptor 2). PHENOTYPE: Homozygous null mice display increased inflammatory response and chemotaxis after exposure to anaphylatoxins. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
