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Protein Coding Gene : Fxyd4 FXYD domain-containing ion transport regulator 4
Primary Identifier  MGI:1889005 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  108017
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ATPase binding activity. Predicted to be involved in inorganic cation transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of sodium:potassium-exchanging ATPase complex. Orthologous to human FXYD4 (FXYD domain containing ion transport regulator 4).
PHENOTYPE: Mice homozygous for a targeted null mutation are viable and fertile but exhibit a significant increase in urine volume (and water intake) under Na+ deprivation and K+ loading, as well as lethality after a combination of high-K+ intake and furosemide injection. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 0610008I02 gene,
  • AI267073,
  • Fxyd4,
  • Chif,
  • 0610008I02Rik,
  • FXYD domain-containing ion transport regulator 4,
  • EST AI267073,
  • MGI:1889805,
  • MGI:1925611
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6 Pathways

Trail: ProteinCodingGene

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Expression

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Phenotype

Genes/Features --> Phenotypes (MP terms)

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Mouse features --> Human diseases

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