| Type | MGI:General | Description | mitochondria consume less oxygen in response to ADP (lower state III respiration) and in response to the uncoupler carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (maximal respiration) compared to wild-type mice, resulting in lower spare respiratory capacity reduction of Complex I activity mitochondrial membrane potential in cells isolated from brains is about 35% lower than in wild-type mice, although this is not statistically significant |
