| First Author | Nakajima H | Year | 1987 |
| Journal | FEBS Lett | Volume | 223 |
| Issue | 1 | Pages | 113-6 |
| PubMed ID | 2822475 | Mgi Jnum | J:51711 |
| Mgi Id | MGI:1326762 | Doi | 10.1016/0014-5793(87)80519-7 |
| Citation | Nakajima H, et al. (1987) Cloning of human muscle phosphofructokinase cDNA. FEBS Lett 223(1):113-6 |
| abstractText | Three overlapping cDNA clones for human muscle phosphofructokinase (HMPFK) covering the complete coding sequence were isolated. The sequence included a poly(A) tail, a 399 bp 3'-untranslated region, a 2337 bp coding region for 779 amino acid residues and a part of the 5'- untranslated region. Homologies between HMPFK and rabbit muscle phosphofructokinase (RMPFK) were 96% of the amino acids and 89% of the nucleotides in the coding region. Like RMPFK, HMPFK also possessed the internal homology between C- and N-halves in its primary structure. Cloning of HMPFK cDNA will help to identify the molecular defect in patients with glycogenosis type VII (HMPFK deficiency). |
