Primary Identifier | MGI:3046926 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(hREN)9Sig |
Strain of Origin | (C57BL/10Ros x C3H/HeRos)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene contained the entire human renin gene. Active renin is released into the plasma, and high levels of human renin expression are detected in kidney, adrenal gland, ovary, testis, lung and adipose tissue. Expression of human renin is not detected in liver or brain. |