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Protein Coding Gene : Sipa1 signal-induced proliferation associated gene 1

Primary Identifier  MGI:107576 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  20469
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTPase activator activity. Acts upstream of or within regulation of cell cycle. Predicted to be located in membrane and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in Golgi apparatus and plasma membrane. Is expressed in several structures, including genitourinary system; heart; immune system; liver; and lung. Used to study chronic myeloid leukemia. Orthologous to human SIPA1 (signal-induced proliferation-associated 1).
PHENOTYPE: Homozygous null mice display chronic myelocytic leukemia in either the chronic phase or blast crisis. [provided by MGI curators]
  • synonyms:
  • SPA-1,
  • Sipa1,
  • MGD-MRK-36148,
  • signal-induced proliferation associated gene 1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For