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Protein Coding Gene : Kdm7a lysine (K)-specific demethylase 7A
Primary Identifier  MGI:2443388 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  338523
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables histone H3K27me2/H3K27me3 demethylase activity and histone H3K9 demethylase activity. Involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A).
PHENOTYPE: Homozygous mutants exhibit abnormal hair follicle, tail, sebaceous gland, rib, and vertebrae morphology and decreased circulating iron levels. [provided by MGI curators]
  • synonyms:
  • expressed sequence BB041802,
  • BB041802,
  • Kdm7a,
  • predicted gene, ENSMUSG00000073143,
  • lysine (K)-specific demethylase 7A,
  • A630082K20Rik,
  • RIKEN cDNA A630082K20 gene,
  • MGI:2141725,
  • jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae),
  • mKIAA1718,
  • ENSMUSG00000073143,
  • MGI:3642369,
  • Jhdm1d
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