| First Author | Tarttelin EE | Year | 2003 |
| Journal | FEBS Lett | Volume | 554 |
| Issue | 3 | Pages | 410-6 |
| PubMed ID | 14623103 | Mgi Jnum | J:86362 |
| Mgi Id | MGI:2679574 | Doi | 10.1016/s0014-5793(03)01212-2 |
| Citation | Tarttelin EE, et al. (2003) Neuropsin (Opn5): a novel opsin identified in mammalian neural tissue. FEBS Lett 554(3):410-6 |
| abstractText | We have cloned and characterised the expression of a new opsin gene, neuropsin (Opn5), in mice and humans. Neuropsin comprises seven exons on mouse chromosome 17. Its deduced protein sequence suggests a polypeptide of 377 amino acids in mice (354 in humans), with many structural features common to all opsins, including a lysine in the seventh transmembrane domain required to form a Schiff base link with retinaldehyde. Neuropsin shares 25-30% amino acid identity with all known opsins, making it the founding member of a new opsin family. It is expressed in the eye, brain, testis and spinal cord. |
