| First Author | Knoepfel L | Year | 1996 |
| Journal | Biol Chem Hoppe Seyler | Volume | 377 |
| Issue | 2 | Pages | 139-45 |
| PubMed ID | 8868069 | Mgi Jnum | J:32968 |
| Mgi Id | MGI:80456 | Doi | 10.1515/bchm3.1996.377.2.139 |
| Citation | Knoepfel L, et al. (1996) Cloning and characterization of the murine B-cell specific transcriptional coactivator Bob1. Biol Chem Hoppe Seyler 377(2):139-45 |
| abstractText | From a murine B-cell cDNA-library we have cloned a cDNA encoding the murine B-cell specific coactivator mBob1. The protein is the murine homologue to the recently described human coactivator Bob1 (hBob1), also referred to as OBF-1 or OCA-B. We have also characterized the genomic mBob1 clone. Analysis of its intron-exon structure has allowed identification of a C-terminal splice variant. mBob1 is B-cell restricted, and is found in all B-cell lines representing different stages of B-cell differentiation. mBob1 interacts with the octamer transcription factors Oct-1 and Oct-2 and stimulates transcription mediated by these factors. |
