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Protein Coding Gene : Cd79a CD79A antigen (immunoglobulin-associated alpha)

Primary Identifier  MGI:101774 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  12518
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables transmembrane signaling receptor activity. Involved in B cell differentiation; B cell proliferation; and B cell receptor signaling pathway. Located in external side of plasma membrane; membrane raft; and multivesicular body. Part of B cell receptor complex. Is expressed in liver. Human ortholog(s) of this gene implicated in agammaglobulinemia 3. Orthologous to human CD79A (CD79a molecule).
PHENOTYPE: Homozygotes for targeted null mutations exhibit arrested development of B cells at the pro-B cell stage due to diminished signaling of the B cell receptor. [provided by MGI curators]
  • synonyms:
  • aimmunoglobulin-associated alpha,
  • immunoglobulin-associated alpha,
  • Ig-alpha,
  • Ly-54,
  • lymphocyte antigen 54,
  • CD79A antigen (immunoglobulin-associated alpha),
  • mb-1,
  • CD79a antigen,
  • MGD-MRK-11997,
  • Iga,
  • Igalpha,
  • Ly54,
  • Ig alpha,
  • MGD-MRK-12040,
  • MGD-MRK-18581,
  • Cd79a

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

3 Driver For