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Allele : Smarcb1<em1Koke> SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; endonuclease-mediated mutation 1, Kornelius Kerl

Primary Identifier  MGI:7520876 Allele Type  Endonuclease-mediated
Gene  Smarcb1 Strain of Origin  (C57BL/6J x DBA)F1
Is Recombinase  false Is Wild Type  false
molecularNote  One of coding cDNA C nucleotides at c.1145-1148 (GRCm39:chr10:g.75732893-75732896) was targeted for deletion using a crRNA (targeting GCCAACACTGCCCCAGCC) and an ssODN template (GGCGAATGAGGCGTCTTGCCAACACTGCCCAGCCTGGTGATGAAGACATCCATGCTCGAC) with CRISPR/Cas9 technology. The deletion causes a frameshift just before the stop codon, which replaces the last 3 endogenous codons with 35 non-endogenous codons.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Smarcb1<1148del>,
  • Smarcb1<1148del>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele