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Allele : Tg(CAG-HSPB1)LPks transgene insertion L, Nick Parkinson
Primary Identifier  MGI:5775102 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(CAG-HSPB1)LPks
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene comprises the coding sequence for wild-type human heat shock protein family B (small) member 1 (HSPB1) downstream of the "CAG promoter" -- which consists of the cytomegalovirus immediate early (CMV-EI) enhancer followed by a 1.3-kb DNA segment including the promoter, first exon and first intron of the chicken beta-actin gene, with the 3' splice junction sequence replaced by that of the rabbit hemoglobin beta gene -- and followed by the rabbit beta-hemoglobin polyadenylation signal and 3' flanking sequence. Heterozygous mice of this low copy number line carry approximately 25 copies of the transgene.
  • mutations:
  • Insertion
  • synonyms:
  • PCAGGS-HSP27-WT-LOW-COPY,
  • chk.actin-HSP27 (WT),
  • HSP27 WT Low copy line,
  • chk.actin-HSP27 (WT),
  • HSP27 WT Low copy line,
  • PCAGGS-HSP27-WT-LOW-COPY
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0 Mutation Involves

Phenotype

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