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Allele : Kdm1a<tm1.1Sho> lysine (K)-specific demethylase 1A; targeted mutation 1.1, Stuart Orkin

Primary Identifier  MGI:5514399 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Kdm1a
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a single loxP site followed by a frt-flanked neomycin resistance (neo) cassette upstream of exon 5, and a second loxP site downstream of exon 6. Exons 5 and 6 encode a flavin adenine dinucleotide binding site and the N-terminal portion of the amine oxidase domain, both required for enzymatic activity. FLPe-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion
  • synonyms:
  • LSD1<fl/fl>,
  • LSD1<fl/fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

19 Publication categories

Trail: Allele