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Allele : Pck1<tm1Mgn> phosphoenolpyruvate carboxykinase 1, cytosolic; targeted mutation 1, Mark A Magnuson

Primary Identifier  MGI:2449282 Allele Type  Targeted
Attribute String  Conditional ready, Hypomorph Gene  Pck1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP-flanked neomycin selection cassette was inserted into intron 3 and a single loxP site was inserted into intron 5. Activity and protein mass assays on protein derived from kidney and liver of fasted homozygous mice demonstrated that this allele behaves as a hypomorph, retaining about 10-20% of normal activity.
  • mutations:
  • Insertion
  • synonyms:
  • pck<lox+neo>,
  • pck<lox+neo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele