| First Author | Bellon SF | Year | 1997 |
| Journal | Nat Struct Biol | Volume | 4 |
| Issue | 7 | Pages | 586-91 |
| PubMed ID | 9228952 | Mgi Jnum | J:159276 |
| Mgi Id | MGI:4442154 | Doi | 10.1038/nsb0797-586 |
| Citation | Bellon SF, et al. (1997) Crystal structure of the RAG1 dimerization domain reveals multiple zinc-binding motifs including a novel zinc binuclear cluster. Nat Struct Biol 4(7):586-91 |
| abstractText | The crystal structure of the dimerization domain of the V(D)J recombination-activating protein, RAG1, was solved using zinc anomalous scattering. The structure reveals an unusual combination of multi-class zinc-binding motifs, including a zinc RING finger and a C2H2 zinc finger, that together from a single structural domain. The domain also contains a unique zinc binuclear cluster in place of a normally mononuclear zinc site in the RING finger. Together, four zinc ions help organize the entire domain, including the two helices that form the dimer interface. |
