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Publication : Assignment of the human intestinal Na+/glucose cotransporter gene (SGLT1) to the q11.2----qter region of chromosome 22.

First Author  Hediger MA Year  1989
Journal  Genomics Volume  4
Issue  3 Pages  297-300
PubMed ID  2714793 Mgi Jnum  J:9755
Mgi Id  MGI:58212 Doi  10.1016/0888-7543(89)90333-9
Citation  Hediger MA, et al. (1989) Assignment of the human intestinal Na+/glucose cotransporter gene (SGLT1) to the q11.2----qter region of chromosome 22. Genomics 4(3):297-300
abstractText  The chromosomal location of the human intestinal Na+/glucose cotransporter gene (SGLT1) was determined using human cDNA and genomic probes for this transporter gene. Southern blot analysis of genomic DNA from 15 mouse-human somatic cell hybrids showed that the human gene for this transporter resides on chromosome 22. Analysis of hamster-human hybrids selectively retaining chromosome 22 or a portion of it allowed specific assignment of the locus to the q11.2----qter region of chromosome 22. A restriction fragment length polymorphism was identified with EcoRI.
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