First Author | Hediger MA | Year | 1989 |
Journal | Genomics | Volume | 4 |
Issue | 3 | Pages | 297-300 |
PubMed ID | 2714793 | Mgi Jnum | J:9755 |
Mgi Id | MGI:58212 | Doi | 10.1016/0888-7543(89)90333-9 |
Citation | Hediger MA, et al. (1989) Assignment of the human intestinal Na+/glucose cotransporter gene (SGLT1) to the q11.2----qter region of chromosome 22. Genomics 4(3):297-300 |
abstractText | The chromosomal location of the human intestinal Na+/glucose cotransporter gene (SGLT1) was determined using human cDNA and genomic probes for this transporter gene. Southern blot analysis of genomic DNA from 15 mouse-human somatic cell hybrids showed that the human gene for this transporter resides on chromosome 22. Analysis of hamster-human hybrids selectively retaining chromosome 22 or a portion of it allowed specific assignment of the locus to the q11.2----qter region of chromosome 22. A restriction fragment length polymorphism was identified with EcoRI. |