Primary Identifier | MGI:6356541 | Allele Type | Endonuclease-mediated |
Attribute String | Not Specified | Gene | Cd274 |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR mediated recombination introduced two nucleotide substitutions of a TA to GC resulting in a Y56A missense mutation. This mutation prevents the formation of the cis-CD274/CD80 duplex. |