Primary Identifier | MGI:5439169 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Gpr37l1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A single loxP site was inserted upstream of exon 1 and a floxed neomycin resistance cassette was inserted in intron 1. Cre-mediated recombination removed the neo cassette and exon 1. Northern blot analysis confirmed the absence of transcript expression. Western blot analysis confirmed the absence of protein expression in the cerebellum. |