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Protein Coding Gene : St6galnac3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

Primary Identifier  MGI:1341828 Organism  mouse, laboratory
Chromosome  3 NCBI Gene Number  20447
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Predicted to be involved in ceramide metabolic process; glycoprotein metabolic process; and oligosaccharide metabolic process. Predicted to act upstream of or within lipid metabolic process. Predicted to be located in nucleoplasm. Is expressed in several structures, including exocrine gland; genitourinary system; hemolymphoid system gland; intestine; and nervous system. Orthologous to human ST6GALNAC3 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3).
PHENOTYPE: Mice homozygous for a null allele exhibit no abnormal phenotype. Double homozygotes lacking St6galnac3 and St6galnac4 exhibit lymph node hemorrhage associated with structural disruption of high endothelial venule. [provided by MGI curators]
  • synonyms:
  • St6galnac3,
  • ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3,
  • sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) C,
  • Siat7c,
  • ST6GalNAc III

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