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Allele : Mapt<tm2(RHOA*)Klt> microtubule-associated protein tau; targeted mutation 2, Kerry Lee Tucker

Primary Identifier  MGI:4442944 Allele Type  Targeted
Attribute String  Conditional ready, Dominant negative, Humanized sequence, Inserted expressed sequence Gene  Mapt
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 1 was replaced with a vector containing a floxed STOP cassette, HA-tagged human cDNA with a nucleotide substitution resulting in the amino acid substitution of threonine with asparagine at position 19, and a neo cassette. Cre mediated recombination is required for the expression of a dominant-negative form.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele