Primary Identifier | IPR015665 | Type | Family |
Short Name | SOST |
description | Sclerostin (SOST) is a negative regulator of bone growth that acts through inhibition of Wnt signalling and bone formation []. Mutations in the SOST gene have been linked to several bone diseases, such as sclerosteosis 1 (SOST1)3 [], van Buchem disease (VBCH) []and craniodiaphyseal dysplasia autosomal dominant (CDD) []. |