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Protein Domain : Sclerostin

Primary Identifier  IPR015665 Type  Family
Short Name  SOST
description  Sclerostin (SOST) is a negative regulator of bone growth that acts through inhibition of Wnt signalling and bone formation []. Mutations in the SOST gene have been linked to several bone diseases, such as sclerosteosis 1 (SOST1)3 [], van Buchem disease (VBCH) []and craniodiaphyseal dysplasia autosomal dominant (CDD) [].

0 Child Features

1 Parent Features

1 Protein Domain Regions