Primary Identifier | MGI:5520081 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Pcdh17 |
Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Sequence encoding a part of the extracellular cadherin domain exon 1 was replaced with a lox71 site, lacZ gene, polyadenylation sequence, FRT site, neomycin resistance cassette, FRT site, loxP site and polyadenylation sequence. Cre-mediated recombination removed the lacZ and neomycin resistance cassette. Western blot analysis confirmed the absence of protein expression in the anterior and posteror striatum. |