Primary Identifier | MGI:5752774 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Rnf213 |
Transmission | Germline | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A G to A missense mutation results in the amino acid substitution of arginine for lysine at position 4828 (R4828K) in exon 61, corresponding to the human R4859K mutation in exon 60. Cre-mediated recombination removed the floxed neomycin cassette inserted upstream of exon 61. |