Primary Identifier | MGI:5698883 | Allele Type | Targeted |
Attribute String | Inducible, Null/knockout, Recombinase | Gene | Sdk2 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The first coding exon was replaced with an inducible cre recombinase gene (cre/ERT2) epitope tagged with six tandem copies of the Myc tag. Cre-mediated recombination removed the floxed neomycin resistance cassette. Immunohistochemistry confirmed the absence of protein expression in the retina from P30. |