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Protein Coding Gene : Nmb neuromedin B

Primary Identifier  MGI:1915289 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  68039
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable neuromedin B receptor binding activity and neuropeptide hormone activity. Involved in several processes, including antiviral innate immune response; positive regulation of osteoclast proliferation; and regulation of cytokine production. Located in extracellular space and neuron projection. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in obesity. Orthologous to human NMB (neuromedin B).
PHENOTYPE: Mice homozygous for a knockout allele exhibit attenuated scratching in response to histamine, compound 48/80 and 5-HT. [provided by MGI curators]
  • synonyms:
  • 3110023K12Rik,
  • RIKEN cDNA 3110023K12 gene,
  • neuromedin B,
  • Nmb

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For