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Protein Coding Gene : Serpina5 serine (or cysteine) peptidase inhibitor, clade A, member 5

Primary Identifier  MGI:107817 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  268591
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable enzyme binding activity; ion binding activity; and serine-type endopeptidase inhibitor activity. Involved in spermatogenesis. Predicted to be located in several cellular components, including external side of plasma membrane; extracellular exosome; and secretory granule. Predicted to be part of several cellular components, including protein C inhibitor-KLK3 complex; protein C inhibitor-PLAT complex; and protein C inhibitor-PLAU complex. Predicted to be active in extracellular space. Is expressed in several structures, including epithelium; genitourinary system; gut; musculoskeletal system; and skin. Orthologous to human SERPINA5 (serpin family A member 5).
PHENOTYPE: Mice homozygous for disruptions in this gene are phenotypically normal with the exception that males are infertile. [provided by MGI curators]
  • synonyms:
  • Pci,
  • serine (or cysteine) peptidase inhibitor, clade A, member 5,
  • antitrypsin,
  • Serpina5,
  • alpha-1 antiproteinase,
  • protein C inhibitor,
  • PAI-3,
  • MGD-MRK-36394

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For