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Protein Coding Gene : Nsl1 NSL1, MIS12 kinetochore complex component
Primary Identifier  MGI:2685830 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  381318
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to be involved in cell division and mitotic sister chromatid segregation. Predicted to be located in kinetochore and nuclear speck. Predicted to be part of MIS12/MIND type complex. Orthologous to human NSL1 (NSL1 component of MIS12 kinetochore complex).
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality prior to organogenesis. In vitro outgrowth assays show that embryos fail to hatch from the zona pellucida and die after 3 days in culture, never forming blastocysts. [provided by MGI curators]
  • synonyms:
  • MGI:2684951,
  • 4833432M17Rik,
  • AI451597,
  • MGI:2138254,
  • RIKEN cDNA 4833432M17 gene,
  • gene model 105, (NCBI),
  • gene model 984, (NCBI),
  • Gm105,
  • NSL1, MIS12 kinetochore complex component,
  • LOC381318,
  • Gm984,
  • expressed sequence AI451597,
  • Nsl1
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Trail: ProteinCodingGene

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