|  Help  |  About  |  Contact Us

Protein Domain : RNA-splicing ligase, RtcB

Primary Identifier  IPR001233 Type  Family
Short Name  RtcB
description  RctB is a RNA ligase that mediates the joining of broken tRNA-like stem-loop structures in case of tRNA damage. It probably participates to tRNA restriction-repair by ligating broken tRNA-like stem-loop structures with 2',3'-cyclic phosphate and 5'-OH ends to form a splice junction with a 2'-OH, 3',5'-phosphodiester [, , , ]. In worms, this protein has as a neuroprotective role in the age-dependent degeneration of dopamine neurons [].

2 Child Features

0 Parent Features

6 Protein Domain Regions