| Primary Identifier | MGI:2445066 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 219150 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables telomeric DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of telomere maintenance via telomerase. Located in chromosome, telomeric region and nucleus. Is expressed in several structures, including central nervous system; early conceptus; female reproductive system; limb mesenchyme; and urinary system. Orthologous to human HMBOX1 (homeobox containing 1). PHENOTYPE: Mice homozygous for a gene trapped allele exhibit absence of TERT binding to chromatin as shown by subcellular fractionation analysis of mouse embryonic fibroblasts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
