| Primary Identifier | MGI:99187 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 22702 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within cellular response to leukemia inhibitory factor; germ cell development; and in utero embryonic development. Located in cytoplasm and nucleus. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early conceptus; gonad; tail; and ureter. Orthologous to human ZFP42 (ZFP42 zinc finger protein). PHENOTYPE: Mice homozygous for one knock-out allele exhibit premature age-related male germ cell loss, abnormal sperm morphology, and mild testicular atrophy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
