| Type | MGI:General | Description | senile plaques detected by thioflavin S or the anti-amyloid beta antibody, 3D6, as early as 4 months of age plaques are restricted to cortex and hippocampus at time points up to 12 months of age plaques increase in number and size over time exhibits an overall increase in soluble and insoluble amyloid beta peptide 40 and 42 between 4 and 12 months |
