| First Author | Périer F | Year | 1994 |
| Journal | FEBS Lett | Volume | 351 |
| Issue | 2 | Pages | 286-90 |
| PubMed ID | 8082782 | Mgi Jnum | J:20181 |
| Mgi Id | MGI:68293 | Doi | 10.1016/0014-5793(94)00879-5 |
| Citation | Perier F, et al. (1994) Identification of a novel mammalian member of the NSF/CDC48p/Pas1p/TBP-1 family through heterologous expression in yeast. FEBS Lett 351(2):286-90 |
| abstractText | Two suppressors of the growth deficiency of a potassium transport mutant of Saccharomyces cerevisiae were isolated from a mouse cDNA expression library. These suppressors, SKD1 and SKD2 (suppressor of K+ transport growth defect), were cDNAs encoding members of a family of ATPases involved in membrane fusion (N-ethylmaleimide-sensitive fusion protein, NSF), cell division cycle regulation (CDC48p), peroxisome assembly (Pas1p), and transcriptional regulation (TBP-1). The SKD1 protein constitutes a novel member of this family with 49-58% amino acid sequence similarity with other family members, and contains a single ATP binding site. The SKD2 polypeptide is the mouse homolog of NSF. |
