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Publication : MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment.

First Author  Zhang L Year  2012
Journal  Leukemia Volume  26
Issue  11 Pages  2310-6
PubMed ID  22617791 Mgi Jnum  J:193068
Mgi Id  MGI:5467483 Doi  10.1038/leu.2012.137
Citation  Zhang L, et al. (2012) MicroRNAs in erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment. Leukemia 26(11):2310-6
abstractText  MicroRNAs (miRNAs) are a class of small regulatory noncoding RNAs that modulate the expression of their target genes through either mRNA degradation or inhibition of protein translation. In recent years, miRNAs have been shown to be critical regulators of hematopoiesis and have important roles in the differentiation of specific lineages. Here, we summarize our current understanding of miRNAs involved in hematopoiesis with a focus on the role of miRNAs in regulating erythroid and megakaryocytic differentiation and megakaryocyte-erythroid progenitor lineage commitment.
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