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Protein Coding Gene : Ctrl chymotrypsin-like
Primary Identifier  MGI:88558 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  109660
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables peptidase activity. Acts upstream of or within proteolysis. Predicted to be located in extracellular space. Is expressed in brain; embryo; pancreas; and pancreas tip epithelium. Orthologous to human CTRL (chymotrypsin like).
PHENOTYPE: Mice homozygous for a null allele exhibit mice exhibit reduced intrapancreatic chymotrypsin activation but normal response to induced pancreatitis. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1810004D15 gene,
  • chymopasin,
  • chymotrypsin-like,
  • MGI:1913502,
  • 1810004D15Rik,
  • Ctra1,
  • Ctra-1,
  • MGD-MRK-2241,
  • MGI:1915660,
  • AV005227,
  • chymotrypsin A,
  • MGI:2142731,
  • RIKEN cDNA 0910001G08 gene,
  • 0910001G08Rik,
  • MGD-MRK-2242,
  • expressed sequence AV005227,
  • Ctrl
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