First Author | Fuchs M | Year | 1998 |
Journal | Mech Dev | Volume | 70 |
Issue | 1-2 | Pages | 91-109 |
PubMed ID | 9510027 | Mgi Jnum | J:46142 |
Mgi Id | MGI:1197181 | Doi | 10.1016/s0925-4773(97)00179-2 |
Citation | Fuchs M, et al. (1998) Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development. Mech Dev 70(1-2):91-109 |
abstractText | The MAM-subfamily of type II transmembrane protein tyrosine phosphatases (PTPases) currently comprises the enzymes PTPkappa, PTPmu and PCP2. In an effort to elucidate the individual physiological roles of these closely related proteins we performed a detailed analysis of their mRNA transcript distributions at different stages of mouse embryogenesis and postnatal brain development. Our in situ hybridization studies revealed distinct and complementary expression patterns of PTPkappa, PTPmu and PCP2 transcripts. Based on our results and previous reports we discuss MAM-PTPases as a new class of morphoregulatory molecules. |