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Protein Coding Gene : Timd4 T cell immunoglobulin and mucin domain containing 4

Primary Identifier  MGI:2445125 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  276891
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables phosphatidylserine binding activity. Acts upstream of or within apoptotic cell clearance. Predicted to be located in membrane. Is expressed in aorta-gonad-mesonephros; brain; gonad; liver; and lung. Used to study systemic lupus erythematosus. Orthologous to human TIMD4 (T cell immunoglobulin and mucin domain containing 4).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired macrophage phagocytosis, altered macrophage physiology, and increased peritoneal lymphoid and meyloid cell numbers. [provided by MGI curators]
  • synonyms:
  • T cell immunoglobulin and mucin domain containing 4,
  • Timd4,
  • RIKEN cDNA B430010N18 gene,
  • Tim4,
  • TIM-4,
  • B430010N18Rik

Features --> Cross References

Genome

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0 CDSs

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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