Primary Identifier | MGI:1924825 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 69188 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable enzyme binding activity; methylated histone binding activity; and transcription coactivator activity. Involved in several processes, including erythrocyte differentiation; neutrophil activation; and neutrophil mediated immunity. Predicted to be located in nuclear body. Predicted to be part of Rpd3L-Expanded complex; Set3 complex; and euchromatin. Is expressed in several structures, including alimentary system; eye; heart; metanephros; and nervous system. Human ortholog(s) of this gene implicated in autistic disorder and cervical cancer. Orthologous to human KMT2E (lysine methyltransferase 2E (inactive)). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal and postnatal lethality, reduced fertility and growth, and abnormal lymphopoiesis. [provided by MGI curators] |