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Comment :

Type  MGI:General Description  injection of lipopolysaccharide (LPS) in control mice (30 mg/kg) induced 46% lethality by 17h after challenge, whereas mutant mice all survived; at 24 h after LPS injection, survival rate was only 8% for control mice compared with 50% for mutant mice at 20 mg/kg, LPS lethality was 36% for control mice, in contrast to 0% for mutant mice after 24 h treatment