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Protein Coding Gene : Twf1 twinfilin actin binding protein 1
Primary Identifier  MGI:1100520 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  19230
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables actin monomer binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and protein tyrosine kinase activity. Involved in barbed-end actin filament capping; positive regulation of cardiac muscle hypertrophy; and sequestering of actin monomers. Located in several cellular components, including filopodium; myofibril; and perinuclear region of cytoplasm. Colocalizes with ruffle membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human TWF1 (twinfilin actin binding protein 1).
  • synonyms:
  • A6,
  • protein tyrosine kinase 9,
  • Ptk9,
  • Twinfilin-1,
  • Twf1,
  • twinfilin,
  • twinfilin actin binding protein 1,
  • actin monomer-binding protein
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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