| Primary Identifier | MGI:105381 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 16785 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables laminin binding activity. A structural constituent of ribosome. Predicted to be involved in cell-cell adhesion; cytoplasmic translation; and ribosomal small subunit assembly. Located in cytoplasm and nucleus. Part of cytosolic small ribosomal subunit. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Used to study Diamond-Blackfan anemia and arrhythmogenic right ventricular dysplasia 5. Orthologous to human RPSA (ribosomal protein SA). PHENOTYPE: Spontaneous mutants show right ventricular cardiomyocyte degeneration and higher susceptibility to arrhythmia. Homozygous null mice fail to develop past E3.5; heterozygotes show craniofacial defects, low mean corpuscular hemoglobin concentration and reduced insulin content in pancreatic islet cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
