Primary Identifier | MGI:6200374 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Tnfrsf9 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to C transition at base pair 150,929,874 (v38) on chromosome 4, or base pair 9,720 in the GenBank genomic region NC_000070 encoding Tnfrsf9. The mutation corresponds to residue 160 in the mRNA sequence NM_011612 within exon 1 of 8 total exons. The mutation results in a valine to alanine substitution at position 10 (V10A) in the CD137 protein. |