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Publication : Assignment of the gene encoding the latent TGF-beta 1-binding protein (LTBP1) to human chromosome 2, region p12-->q22.

First Author  Stenman G Year  1994
Journal  Cytogenet Cell Genet Volume  66
Issue  2 Pages  117-9
PubMed ID  8287682 Mgi Jnum  J:16758
Mgi Id  MGI:64819 Doi  10.1159/000133680
Citation  Stenman G, et al. (1994) Assignment of the gene encoding the latent TGF-beta 1-binding protein (LTBP1) to human chromosome 2, region p12-->q22. Cytogenet Cell Genet 66(2):117-9
abstractText  Latent transforming growth factor beta 1-binding protein (LTBP1) is an important component of the large latent TGF-beta 1 complex. It plays a role in the assembly and secretion of the latent TGF-beta 1. In this paper we have used a cDNA probe for LTBP1 to determine the chromosomal localization of the human gene. Using a panel of well-defined human x rodent somatic cell hybrid lines, LTBP1 could be assigned to chromosome 2. Further sublocalization of the gene to 2p12-->q22 was achieved using three hybrid lines which contain partially over-lapping fragments of chromosome 2.
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