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Protein Coding Gene : Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Primary Identifier  MGI:99603 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  67155
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including chromatin binding activity; transcription cis-regulatory region binding activity; and transcription coactivator activity. Acts upstream of or within aortic smooth muscle cell differentiation; hematopoietic stem cell homeostasis; and negative regulation of fibroblast proliferation. Located in nucleus. Part of nBAF complex and npBAF complex. Is expressed in several structures, including cerebral cortex; early conceptus; genitourinary system; heart; and vitelline artery. Orthologous to human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2).
PHENOTYPE: Mice homozygous for a targeted mutation in this gene may exhibit infertility and a slightly increased body weight in some genetic backgrounds. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2610209L14 gene,
  • brm,
  • SNF2, sucrose nonfermenting, yeast, homolog,-like 2,
  • Smarca2,
  • MGD-MRK-16388,
  • Snf2l2,
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2,
  • 2610209L14Rik,
  • MGI:1914405

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Canonical gene --> CDSs in specific strains.

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Canonical gene --> Transcripts in specific strains.

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Mouse features --> Functions (GO terms)

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